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What makes a coronary plaque vulnerable to rupture?

A collaborative research team from Imperial College, St Mary’s and the Brompton Hospital has developed novel modelling techniques that can be used to map local haemodynamic stresses in the circulation. Interest is now focused on the more challenging setting of the coronary arteries.

Dr Ryo Torii is using this state-of-the-art technology to develop a combined in vivo imaging and computational technique for use as a predictive diagnostic tool for identifying plaques (the build-up of hardened fatty material in the arteries) that are vulnerable to rupture.

‘Identifying those patients at risk will allow us to use interventions (such as coronary artery stents) to prevent plaque rupture and heart attack.’

Dr Ryo Torii

Dr Ryo Torii